VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Mongolian horse

Scientific Name: Equus caballus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Perissodactyla-> Equidae-> Equus-> Equus

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Middle East respiratory syndrome-related coronavirus

Family: Coronaviridae

Receptor: DPP4

Receptor DPP4 information

Summary: The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. [provided by RefSeq, Apr 2020] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0066 2021.04 iDrop PBMC Normal 12794 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of DPP4 in human tissues   [NCBI]

Expression: Biased expression in small intestine (RPKM 70.7), placenta (RPKM 57.1) and 13 other tissues

Protein expression of DPP4 in human tissues   [Proteinatlas]